Crosslinker UV – QualiCL™ UV Applications
Membrane crosslinking for blotting workflows
Use controlled 254 nm exposure to immobilize DNA/RNA on nylon or nitrocellulose membranes after transfer. This supports downstream hybridization, wash steps, and imaging with more consistent signal retention versus uncontrolled UV sources.
DNA/RNA–protein crosslinking for interaction studies
Apply a defined UV dose to form covalent bonds between nucleic acids and proteins for capture-based workflows and related assays. UV at 254 nm is widely used for nucleic-acid/protein crosslinking in research methods.
UV decontamination and surface sterilization (PCR contamination control)
Run quick UV exposure cycles to reduce nucleic-acid carryover on tools, chambers, and selected lab items. This supports cleaner PCR setups and routine contamination control programs.
UV-based reactions and method development
Use optional wavelengths (365 nm / 312 nm) when protocols specify UVA/UVB exposure windows. This is common in troubleshooting photoreaction sensitivity, optimizing dose response, or adapting legacy protocols to a controlled enclosure.
Blue-light adhesive cutting support (optional module)
Use the blue-light cutting area for safer gel handling workflows where blue-light excitation is preferred over UV for sample integrity. The integrated module supports defined cutting space and stable illumination parameters.
Standards and compliance
- IEC 61010-1 (Safety requirements for electrical equipment for measurement, control, and laboratory use).
- UL 61010-1 (U.S. safety adoption aligned to IEC 61010-1).
- IEC 61326-1 (EMC requirements for laboratory and measurement equipment).
