Theory and Method
This Ultrasonicator uses indirect ultrasonic energy transferred through a coupling medium to sealed tubes held in a multi-hole bracket. Ultrasonic waves create cavitation in the surrounding medium, and that energy disrupts cells or shears biomolecules inside the closed container without probe contact. Adjustable power and duty cycle control shape the intensity, while longer timing supports extended protocols. Low-temperature equipment can be paired to hold a cool environment for heat-sensitive samples.
A typical method starts by selecting the tube type and bracket that matches sample volume. Place sealed tubes into the bracket, set power, duty cycle, and total time, then monitor temperature display during operation. For sensitive proteins or nucleic acids, use cooling support to manage temperature rise during longer runs. After completion, remove tubes and continue to downstream extraction or analysis steps.
