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Nucleic Acid Purification – QualiNAP™ 96

Nucleic Acid Purification – QualiNAP™ 96
Parent Product
Life Science Equipments
Standards
CLSI MM13
ISO 15189
ISO 18385
ISO 20186
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Nucleic Acid Purification – QualiNAP™ 96

Nucleic Acid Purification is the core workflow of QualiNAP™ 96, a high-throughput automated extractor built to purify DNA and RNA from many sample types with minimal hands-on steps. The system uses a magnetic-rod workflow to move bead-bound nucleic acids through lysis, binding, wash, and elution steps inside a deep-well plate format.

It supports 96 or 24 samples per run, plus both standard and large-volume processing, which fits routine molecular testing and batch research workflows.

QualiNAP™ 96 is designed for labs that need fast batch extraction with consistent well-to-well performance. The platform is positioned as an upgraded, higher-capacity system in the same family as smaller instruments, with an emphasis on throughput and automation for clinical gene analysis demand.

It supports purification from sources such as whole blood, virus samples, tissue, plants, bacteria, and cultured cells when paired with the correct reagent kits. A color touchscreen interface and stored programs help standardize extraction steps across operators and shifts.

Nucleic Acid Purification – QualiNAP™ 96 Applications

High-throughput clinical gene testing workflows

Process large batches for molecular diagnostics where consistent timing and reduced manual steps matter. A 96-sample run helps keep turnaround predictable during peak volume.

Viral nucleic acid extraction

Purify viral DNA or RNA from clinical or research samples using compatible magnetic-bead kits. Automated extraction supports repeatable downstream amplification and detection workflows.

Multi-matrix research extraction

Run extraction from diverse matrices such as tissue, plants, bacteria, and cultured cells without changing the core automation concept. Stored programs support method consistency when different teams use the same instrument.

Large-volume sample processing

Handle higher input volumes when your protocol needs larger sample loads or concentrated eluates. The large-volume range supports workflows beyond standard microplate volumes.

Nucleic Acid Purification – QualiNAP™ 96

Standards

  • ISO 20186 series: Pre-examination guidance for molecular IVD specimens, including handling, storage, processing, documentation, and the impact of isolation steps on results.
  • ISO 15189: Requirements for quality and competence in medical laboratories, often used to frame method control and documentation practices.
  • CLSI MM13: Guidance covering specimen collection, transport, storage, and nucleic acid isolation principles for molecular methods. QualiNAP™
  • ISO 18385 (for forensic workflows): Requirements to minimize risk of detectable human DNA contamination in products used for forensic DNA processes.

Nucleic Acid Purification – QualiNAP™ 96 Key Features

  • 96 or 24 sample throughput to match daily batch volume and workflow priorities.
  • Fast run time with typical processing stated at 20–40 minutes, depending on kit and method.
  • Wide processing volume options supporting 20–1000 μL and 100–5000 μL workflows.
  • High bead recovery performance listed at >99% to support strong yield consistency.
  • High-strength permanent magnetic column listed at >4800 GS for stable bead capture.
  • Program control and storage with 12 preset programs and storage listed as ≥100 sets.
  • Reduced manual involvement designed to lower sample-to-sample variation during batch processing.
  • Modular approach supporting different channel configurations and customization options on consumables based on workflow needs.

Theory and Method

Nucleic Acid Purification – QualiNAP™ 96

QualiNAP™ 96 uses a magnetic-rod process with magnetic beads to capture nucleic acids during extraction. After lysis, target DNA or RNA binds to functionalized beads. The instrument moves the bead-bound targets through different reagent wells, then mixes by repeatedly moving the rod sleeve to improve contact and wash efficiency. Wash steps remove inhibitors, and the final elution releases purified nucleic acids into buffer for downstream PCR, RT-PCR, or sequencing preparation.

Nucleic Acid Purification – QualiNAP™ 96 Technical Specification

SpecificationQualiNAP™ 96
Sample throughput96 / 24
Processing volume20–1000 µL / 100–5000 µL
Extraction methodMagnetic rod principle with bead transfer
Processing time20–40 minutes
Magnetic bead recovery rate>99%
Permanent magnetic column>4800 GS
InterfaceColor touchscreen
Program storage≥100 sets; 12 preset programs
Sample types supported (with kits)Whole blood, virus, tissue, plant, bacteria, cultured cells
Nucleic Acid TypeReagent Kit ClassificationSpecificationSample Type
Viral Nucleic AcidViral DNA/RNA Purification Kit32T, 48T, 96TSerum, plasma, lymph, cell-free body fluids, cell culture supernatant, urine, tissue, swabs, or various viral transport media
gDNAWhole Blood Genomic DNA Purification Kit32T, 48T, 96TMammalian, avian, and amphibian whole blood (EDTA, Heparin, etc.)
Dried Blood Spot Genomic DNA Extraction Kit32T, 48T, 96TDried blood spots
Animal Tissue Genomic DNA Kit32T, 48T, 96TLiver, kidney, brain, tail, muscle tissue, etc.
Plant Tissue Genomic DNA Extraction Kit32T, 48T, 96TRoots, stems, flowers, leaves, fruits, etc.
Oral Swab Genomic DNA Extraction Kit32T, 48T, 96TCotton swabs
Saliva Genomic DNA Extraction Kit32T, 48T, 96TSaliva
Stool Genomic DNA Extraction Kit32T, 48T, 96TStool / Feces
Bacterial Genomic DNA Extraction Kit32T, 48T, 96TMicroorganisms, sputum, swab washes, blood, stool, etc.
RNAAnimal Tissue RNA Kit32T, 48T, 96TLiver, kidney, brain, tail, muscle tissue, etc.
Plasmid DNAPlasmid Extraction Kit32T, 48T, 96TBacteria
Product PurificationGel Recovery Kit32T, 48T, 96TAgarose gel electrophoresis samples
PCR Product Purification Kit32T, 48T, 96TPCR amplification products
Nucleic Acid Fragment Recovery Kit32T, 48T, 96TFragmented nucleic acids

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